Promethazine Review

Published: 14th December 2010
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Any good Promethazine review will tell you about its basics, indications, and side effects, among other things. This information can also be found by reading the associated literature.

The drug comes from a family of first-generation H1 receptor antagonists, which in turn is a part of the phenothiazine chemical class. It is widely used as an antihistamine and increasingly being used as a sedative in some countries. Its benefits are also pervasive in treating motion sickness and pains, among other related maladies.

Promethazine is a first-generation drug that means that it has been manufactured after tracking the advantages of similar drugs and after making serious modifications to create a potent formula. It blocks histamine H1 receptors but does so without impeding the secretion of histamine. It has also been found to mildly affect Dopamine production. These properties also have a slightly anti-sedative effect on people taking the drug.

Drowsiness is a common side effect that has been observed in up to 10% of people. Driving and other jobs that require mental attention are strongly discouraged during the potent half-time of the drug. Some doctors advise taking it at night to avoid any incidents but serous allergic reactions may require at least two daily doses.

Other side effects are not as common though some people have complained about dry mouth, cough and sore throat. Diarrhea and vomiting are not included as major side effect as it has been reported in less than 1% of people using the drug. Severe side effects are uncommon and have been reported in a very tiny fraction of people taking the drug. Seizures have been reported in a few people though many among them had preexisting conditions.

Hypersensitivity to the drug is much lower than its counterparts. As it is used as an antihistamine itself, great care has been taken to use a safer formula. Some people may still feel allergic reactions especially if they have preexisting condition. In this case they should contact a medical facility immediately to find the real cause of the symptoms.

Any good Promethazine review will highlight all of these aspects as well as tell you that the drug is available both in the form of tablets and syrup and is equally beneficial for adults and children. It should ideally be used after prescription from a doctor to rule out the possibility of any side effects.

Overall Promethazine is an effective anti-allergenic with minimal side effects, and is being used more commonly these days as a sedative. As with any drug however, care must always be taken with administration to ensure the correct dose is taken.

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